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imagequanttm las 4000 luminescent image analyzer  (Danaher Inc)


Bioz Verified Symbol Danaher Inc is a verified supplier
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    Structured Review

    Danaher Inc imagequanttm las 4000 luminescent image analyzer
    Imagequanttm Las 4000 Luminescent Image Analyzer, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 97/100, based on 6553 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/imagequanttm+4000+image+analyzer/ImageQuant+LAS+4000/pm34226664-133-5-11
    Average 97 stars, based on 6553 article reviews
    imagequanttm las 4000 luminescent image analyzer - by Bioz Stars, 2026-10
    97/100 stars

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    Related Articles

    Expressing:

    Article Title: Decreased ER dependency after acquired resistance to CDK4/6 inhibitors.
    Article Snippet: Background Cyclin-dependent kinase (CDK) 4/6 inhibitors represent a significant advancement in the treatment of estrogen receptor (ER)-positive human epidermal growth factor receptor 2-negative advanced breast cancer.. However, mechanisms of alterations after acquired resistance to CDK4/6 inhibitors and the optimal treatment options are still not established.. Methods Abemaciclib-resistant cell lines were established from the models of estrogen deprivation-resistant cell lines which retained ER expression and activated ER function derived from MCF-7 breast cancer cell lines.

    Western Blot:

    Article Title: Decreased ER dependency after acquired resistance to CDK4/6 inhibitors.
    Article Snippet: Background Cyclin-dependent kinase (CDK) 4/6 inhibitors represent a significant advancement in the treatment of estrogen receptor (ER)-positive human epidermal growth factor receptor 2-negative advanced breast cancer.. However, mechanisms of alterations after acquired resistance to CDK4/6 inhibitors and the optimal treatment options are still not established.. Methods Abemaciclib-resistant cell lines were established from the models of estrogen deprivation-resistant cell lines which retained ER expression and activated ER function derived from MCF-7 breast cancer cell lines.

    Article Title: Quercetin induces tongue squamous cell carcinoma cell apoptosis via the JNK activation-regulated ERK/GSK-3α/β-mediated mitochondria-dependent apoptotic signaling pathway
    Article Snippet: .. The antibody-reactive bands were revealed using an Immobilon ® Western Chemiluminescent HRP substrate kit (MilliporeSigma) and analyzed using a luminescent image analyzer (ImageQuantTM LAS-4000; GE Healthcare Bio-Sciences). .. The bands underwent densitometric analysis using ImageJ version 1.50d software (National Institutes of Health).

    Blocking Assay:

    Article Title: Roles of ERK/Akt signals in mitochondria-dependent and endoplasmic reticulum stress-triggered neuronal cell apoptosis induced by 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a major active metabolite of bisphenol A.
    Article Snippet: Bisphenol A (BPA) is recognized as a harmful pollutant in the worldwide.. Growing studies have reported that BPA can cause adverse effects and diseases in human, and link to a potential risk factor for development of neurodegenerative diseases (NDs).. 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene (MBP), which generated in the mammalian liver after BPA exposure, is a major active metabolite of BPA.

    Article Title: 4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a Major Active Metabolite of Bisphenol A, Triggers Pancreatic β-Cell Death via a JNK/AMPKα Activation-Regulated Endoplasmic Reticulum Stress-Mediated Apoptotic Pathway
    Article Snippet: .. After blocking, the membranes were incubated with the specific antibodies against caspase-3, caspase-7, caspase-9, PARP, p-JNK, p-AMPKα, JNK, AMPKα, GPR 78, GRP 94, CHOP, caspase-12, and β-actin in 0.1% PBST (1:1000) for 1 h. After three additional washes in 0.1% PBST (15 min each), the respective HRP-conjugated secondary antibodies were applied (in 0.1% PBST (1:2500)) for 1 h. The antibody-reactive bands were detected using enhanced chemiluminescence reagents (PierceTM, Thermo Fisher Scientific Inc., Waltham, MA, USA) and analyzed using a luminescent image analyzer (ImageQuantTM LAS-4000; GE Healthcare Bio-Sciences, Uppsala, Sweden). ..

    Incubation:

    Article Title: Roles of ERK/Akt signals in mitochondria-dependent and endoplasmic reticulum stress-triggered neuronal cell apoptosis induced by 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a major active metabolite of bisphenol A.
    Article Snippet: Bisphenol A (BPA) is recognized as a harmful pollutant in the worldwide.. Growing studies have reported that BPA can cause adverse effects and diseases in human, and link to a potential risk factor for development of neurodegenerative diseases (NDs).. 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene (MBP), which generated in the mammalian liver after BPA exposure, is a major active metabolite of BPA.

    Article Title: 4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a Major Active Metabolite of Bisphenol A, Triggers Pancreatic β-Cell Death via a JNK/AMPKα Activation-Regulated Endoplasmic Reticulum Stress-Mediated Apoptotic Pathway
    Article Snippet: .. After blocking, the membranes were incubated with the specific antibodies against caspase-3, caspase-7, caspase-9, PARP, p-JNK, p-AMPKα, JNK, AMPKα, GPR 78, GRP 94, CHOP, caspase-12, and β-actin in 0.1% PBST (1:1000) for 1 h. After three additional washes in 0.1% PBST (15 min each), the respective HRP-conjugated secondary antibodies were applied (in 0.1% PBST (1:2500)) for 1 h. The antibody-reactive bands were detected using enhanced chemiluminescence reagents (PierceTM, Thermo Fisher Scientific Inc., Waltham, MA, USA) and analyzed using a luminescent image analyzer (ImageQuantTM LAS-4000; GE Healthcare Bio-Sciences, Uppsala, Sweden). ..



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